Drug treatment by gonadorelin analogues
There are a number of drugs that are used for this treatment:
These drugs mimic menopause by blocking the hormone (gonadotrophin releasing hormone) that is responsible for the production of oestrogen, ampoule the female hormone. These are known as gonadorelin analogues.
They induce rapid menopause by blocking oestrogen production with the result that the blood levels to the fibroid drop and the fibroids get smaller, as they would after menopause.
This is only a temporary treatment for fibroids, sometimes used to reduce them before surgery or menopause. However, drugs should not be used for longer than 6 months and should not be repeated.
The side effects are menopausal-like - hot flushes, increased sweating, vaginal dryness, loss of libido, osteoporosis, mood swings, memory loss and hypersensitivity reactions. Some gynaecologists will not use these drugs, as the side effects are so unpleasant.
When drug treatment stops the fibroids return to their pre-treatment size within 24 weeks.
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Thanks to all who took part in our survey about the information and choices for their fibroid treatment. Please click here for the Patient Information and Choice Survey report and here for our report on access to UFE treatment with The Medical Technology Group and All Party Parliamentary Group on Improving Patient Access to Medical Technologies.
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